Drug handling: Information sources

Last updated: Sunday, July 05, 2015

Drug handling problems can be complex, but for straightforward clinical situations concerned with sampling times and so forth, check to see if you have an in-house policy at your hospital. Alternatively try the TDM table we have produced here for general guidance. Most SPCs have TDM information for drugs with a narrow therapeutic range.

       © Crown copyright 2017
Martindale, Dollery’s Therapeutic Drugs, and Micromedex, can be helpful for determining a range of kinetic data including time to onset of action, protein binding, Vd, metabolism and excretion.

There are a number of pharmacokinetics books available, most are fairly in-depth and so consult these only after you’ve tried the above; examples include Basic Clinical Pharmacokinetics by Winter (Lippincott Williams and Wilkins) and Clinical Pharmacokinetics by Dhillon and Kostrzewski (Pharmaceutical Press).

Embase and then Medline may be helpful for more complex situations.

Be careful about conducting a general internet search on this subject. If you do, you may like to look at our brief guide to evaluating websites about medicines.

Presenting your answer 

Once you’ve asked sufficient questions, gathered the information required and assessed it, you’ll need to provide an answer. We can offer you some general guidance on answering clinical problems.