Liver: suggested questions

Last updated: Sunday, July 12, 2015

They may not apply to every situation you come across, but here are some questions you should be thinking about in practice.

The Medicine


If requesting advice on dosage or suitability of a drug in hepatic dysfunction:

  • What is the indication for the drug, and have alternatives been considered?
  • What agent would normally be used if the patient did not have liver dysfunction?

If drug-induced hepatotoxicity is suspected:

  • Is the patient currently taking the drug in question, or if not when did they stop?
  • What other drugs are being taken or have been taken recently?

The Patient


  • Clinical condition of the patient, age, and presumed diagnosis.
  • Results of LFTs (including clotting screen), biopsies and other diagnostic liver tests.
  • Are the LFTs stable or changing?
  • What is the patient’s renal function?

Going Forward


  • Who is in a position to change therapy if necessary and who will be monitoring the patient?
  • How might any advice given change if the patient’s liver function deteriorates further?