On-call scenario 5: Resolution
What an on-call pharmacist could advise...
The study that you have found on Embase is very small, but it advises that the dose of ceftriaxone does not need to be adjusted in patients on CVVH. It explains that the drug is cleared more effectively than the protein binding would predict. This is backed up by what you found in the Renal Drug Database.Therefore you decide to advise the doctor that the patient may be given a second dose of ceftriaxone as per microbiology advice.
Follow up
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If this scenario has made you a little concerned about answering a question like this when you're on-call, then why not look through the Renal tutorial to refresh your knowledge?